OPTIMISED RESEARCH LABS
ORL IBUTAMOREN MK 677
ORL IBUTAMOREN MK 677
DESCRIPTION
SARMS MK 677
SARM MK677, also known as Ibutamoren, Oratrope, or Nutrobal (molecular weight 528.662), is a ghrelin agonist that acts on the pituitary gland as a human growth hormone secretagogue and is sometimes classified along with selective androgen receptor modulators (SARMs).
It differs from Ghrelin itself in that it is not a peptide but rather a spiropiperidine. Since it can cross the blood-brain barrier, MK-677 functions as a neuropeptide in the central nervous system.
MK-677 Benefits from Clinical Research
MK 677 has displayed multiple effects in vivo, including:
- Increase in GH levels
- Increase in muscle mass and lean body mass
- Reduced body fat
- Increase in bone density
- Faster muscle growth
- Improved immune function
- Improved REM sleep
- Increased appetite
- Reversal of growth hormone deficiency
- Alleviation of pathology related to beta amyloid
Potential MK677 Side Effects
However, it must be emphasized that MK 677 has not been approved by the Food and Drug Administration (FDA) for human consumption and efficacy. The severity of documented side effects like water retention, angiogenesis, and changes in blood pressure and blood sugar are still being determined. Potential drug interactions are also unknown at this time so caution is critical with this compound.
Since it has a very long half life, there is a some concern that sustained administration of MK-677 can overstimulate or desensitize the ghrelin receptor in the human brain. Perhaps the most immediately noticeable side effect of Ibutamoren at this time is a significant increase in appetite and hunger.
CONCENTRATION
60 capsules - 12.5mg per capsule
SHIPPING
UK
Royal Mail Tracked 24 - £4.49
Royal Mail Tracked 48 - £3.49
FREE SHIPPING OVER £50
EUROPE
Royal Mail International Tracked £8.00
FREE SHIPPING OVER £200
DISCLAIMER
This material is sold for use in laboratory research only. Terms of sale apply. Not for human consumption, nor for medical, veterinary or household use.
FAQs
There is presently no evidence that MK677 compromises the body’s natural release of GH long term. More information may be available in the future.
Can MK 677 trigger gynecomastia?
A two-year human study on MK677 found that subjects experienced a significant decrease in the risk of developing gynecomastia when compared to the administration of injectable Growth Hormone.
Does MK 677 suppress testosterone?
MK-677 does not act on the feedback loop for testosterone in the body and is not expected to suppress natural testosterone levels.
Studies have demonstrated the ability of MK 677 (aka Nutrobal) to raise endogenous levels of HGH and IGF-1.