What Are SARMs? 

Selective Androgen Receptor Modulators (SARMs) are research compounds designed to selectively bind to androgen receptors in the body. Unlike anabolic steroids, which affect multiple tissues, SARMs primarily target muscle and bone.

Why Safety Is a Key Concern

SARMs are often marketed as a “safer alternative” to steroids, but the reality is more complex. While research suggests potential therapeutic uses, most SARMs are not approved for human use outside controlled trials.

The U.S. Food and Drug Administration (FDA) has issued warnings about SARMs in supplements due to potential risks such as:

• Liver toxicity
• Increased cardiovascular risks
• Hormonal imbalances
• Mood swings and psychiatric effects

🔗 Source: FDA Warning on SARMs

Documented Side Effects of SARMs

1. Liver Damage

Some SARMs may elevate liver enzymes, indicating stress on the liver. This is one of the most consistently reported risks in research.

🔗 See research: SARMs Safety Study – PubMed

2. Hormonal Suppression

SARMs can reduce natural testosterone production, causing fatigue, reduced libido, and difficulty maintaining muscle gains after discontinuation.

3. Cardiovascular Risks

Some SARMs are linked to unfavourable cholesterol changes. Long-term effects on heart health are still not fully understood.

4. Other Possible Effects

• Mood changes, aggression, and sleep disturbances (anecdotally reported)
• Joint or tendon discomfort

SARMs vs Steroids: Are They Safer?

SARMs are often promoted as a “milder” alternative to anabolic steroids. While they may carry fewer side effects in theory, research is limited, and misuse or long-term use can still be risky.

👉 Learn more: SARMs vs Steroids

Legal Status and Regulations

In the UK, SARMs are classified as research chemicals, not dietary supplements, meaning they are not approved for human consumption.

The World Anti-Doping Agency (WADA) also lists SARMs as prohibited substances in sports.

🔗 Source: WADA Prohibited List

👉 Read more: Are SARMs Legal in the UK?

Final Thoughts: Why Safety Matters

SARMs continue to attract attention in the fitness world, but safety must be the top priority. Potential side effects—from liver toxicity to hormonal suppression—highlight the importance of caution and responsible sourcing.

At SMART SARMS, we believe in transparency, quality, and education, helping researchers and informed buyers understand both the potential and the risks.

👉 Browse our full range: Shop SARMs UK

FAQ

Q1: What are SARMs used for?
SARMs are being studied for muscle wasting, osteoporosis, and performance enhancement. Most are not approved for general human use.

Q2: Are SARMs safer than steroids?
SARMs may carry fewer side effects than anabolic steroids, but long-term safety is not well studied, and misuse is risky.

Q3: What are the side effects of SARMs?
Side effects can include liver stress, hormonal suppression, cardiovascular changes, mood swings, and joint discomfort.

Q4: Are SARMs legal in the UK?
SARMs are classified as research chemicals, not dietary supplements, and are not approved for human consumption.